TAIYO NIPPON SANSO -The Gas Professionals-

We specially designed and constructed a dedicated plant composed of an ultra-pure oxygen production unit and an isotope separation unit to produce high-quality Water-¹⁸O.

We manufacture Water-¹⁸O according to GMP (ICH:Q7A).
Sterility and purity are strictly controlled throughout the manufacturing process.

: Taiyo Nippon Sanso has provided continuous support for PET imaging since the early stage of development and has strived to provide the best quality cyclotron target for PET diagnostic reagent demanded by clinical sites. The result is our high quality 98atom% Water-¹⁸O, manufactured by the cryogenic distillation of ultra pure oxygen. We always lead the way in the highest quality products to fulfill the needs of the PET community.

Superior Properties of our water-¹⁸O: Enrichment:>98 atom%
Capacity:>100kg/year
High Quality: Water-¹⁸O is produced through the reaction of Ultra-Pure-¹⁸O₂ with ultra pure hydrogen.
Quality Assurance: Our quality is assured by our GMP-based production/quality control.
Specification: Formula：H₂¹⁸O
Chemical purity：>99.99%
Molecular weight：19.98
Package size：10grams, 20grams and 50grams
Container：glass vial septum top and aluminum crimp seal

Test	Specification	Method
Oxygen-¹⁸O	≧98.0 atom%	MS
Oxygen-¹⁷O	＜2.0 atom%	MS
Oxygen-¹⁶O	＜2.0 atom%	MS
Copper	＜1 mg/L	ICP-MS
Calcium	＜1 mg/L	ICP-MS
Iron	＜0.1 mg/L	ICP-MS
Zinc	＜1 mg/L	ICP-MS
Potassium	＜1 mg/L	ICP-MS
Sodium	＜2 mg/L	ICP-MS
Magnesium	＜1 mg/L	ICP-MS
Ammonium	＜1 mg/L	IC
Chloride	＜1 mg/L	IC
Bromide	＜1 mg/L	IC
Fluoride	＜1 mg/L	IC
Sulfate	＜1 mg/L	IC
Nitrate	＜1 mg/L	IC
Iodide	＜1 mg/L	IC
Phosphate	＜1 mg/L	IC
pH	5.5-8.0	ｐH Meter
Conductivity	＜0.3 mS/m	Conductivity Meter
Total Organic Carbon	＜5 mg/L	TOC Analyzer
Standard Plate Count	＜1 /mL	Membrane Filter
Pyrogenicity	＜0.25 EU/mL	LAL
Appearance	Clear, Colorless, No visible object